• Caris Life Sciences to Present Data on Clinical Benefit of Caris Molecular Intelligence at 2016 Gastrointestinal Cancers Symposium

    Data Provides Insights on Precision Cancer Care in Rare and Aggressive Malignancies

     IRVING, Tex., Jan. 21, 2016 Caris Life Sciences®, a leading biotechnology company focused on fulfilling the promise of precision medicine, announced today that it will present five data abstracts at the 2016 Gastrointestinal Cancers Symposium, January 21-23, 2016 in San Francisco, Calif.

    Each of the five studies being presented used Caris Molecular Intelligence® (CMI), the company’s panomic, comprehensive, and patented tumor profiling product, to facilitate biomarker identification and molecular characterization of gastrointestinal cancers across different subtypes and age groups. Because Caris Molecular Intelligence utilizes multiple advanced technologies to examine DNA, RNA and proteins, investigators were able to gain a better molecular understanding of rare and aggressive malignancies. CMI also informs physicians regarding therapeutic options of potential benefit and also potential lack of benefit, including immunotherapies, targeted therapies and chemotherapies, in patients with different subtypes of gastrointestinal cancers.

    Following is a schedule of Caris Life Sciences’ poster presentations:

    Title: Tumor profiling of 431 pancreatic tumors from elderly patients

    Date and Time: Friday January 22, 12:30 p.m. – 2:00 p.m.

    Abstract: 257

    Poster Display Location: Moscone Center, Level 1, West Hall

    Session: Poster Session B – Cancers of the Pancreas, Small Bowel, and Hepatobiliary Tract; Board D3

    Authors: Joanne Xiu, Kevin Rakszawski, Sandeep Reddy, Yuxia Jia

    Research Partner: Penn State Milton S. Hershey Medical Center

    Title: PD-1/PD-L1 expression and molecular associations in HPB malignancies

    Date and Time: Friday January 22, 12:30 p.m. – 2:00 p.m.

    Abstract: 289
    Poster Display Location: 
    Moscone Center, Level 1, West Hall

    Session: Poster Session B – Cancers of the Pancreas, Small Bowel, and Hepatobiliary Tract; Board E13

    Authors: Kabir Mody, Rebecca Feldman, Sandeep Reddy, Gina Reynolds, Jessica McMillan, Elizabeth Johnson

    Research Partner: Mayo Clinic (Florida)

    Title: Molecular characterization of colorectal tumors in young patients compared with older patients and impact on outcome

    Date and Time: Saturday January 23, 12:30 p.m. – 2:00 p.m.

    Abstract: 505

    Poster Display Location: Moscone Center, Level 1, West Hall

    Session: Poster Session C – Cancers of the Colon, Rectum, and Anus; Board A18

    Authors: Arielle Heeke, Joanne Xiu, Sandeep Reddy, Jiji Jiang, Hongkun Wang, John Marshall, Mohamed Salem

    Research Partner:  Lombardi Comprehensive Cancer Center, Georgetown University

    Title: Molecular profiling of appendix-derived pseudomyxoma peritonei (PMP)

    Date and Time: Saturday January 23, 12:30 p.m. – 2:00 p.m.

    Abstract:  571
    Poster Display Location: 
    Moscone Center, Level 1, West Hall

    Session: Poster Session C – Cancers of the Colon, Rectum, and Anus; Board D20

    Authors: Elizabeth Gleeson, Rebecca Feldman, Sherri Millis, Beth Mapow, Lynn Mackovick, Sandeep Reddy, Wilbur Bowne

    Research Partner: Drexel University College of Medicine

    Title: TOPO1 expression in primary and metastatic GI cancers

    Date and Time: Saturday January 23, 12:30 p.m. – 2:00 p.m.

    Abstract:  643

    Poster Display Location: Moscone Center, Level 1, West Hall

    Session: Poster Session C – Cancers of the Colon, Rectum, and Anus; Board H4

    Authors: Michael Castro, Rebecca Feldman, Sandeep Reddy

    Research Partner: Personalized Cancer Medicine, PLLC

    About Caris Life Sciences®

    Founded by David D. Halbert in 2008, Caris Life Sciences® is a leading biotechnology company focused on fulfilling the promise of precision medicine through quality and innovation. Caris Molecular Intelligence®, the company’s healthcare information and comprehensive tumor profiling product, with more than 80,000 patients profiled, provides oncologists with the most clinically actionable treatment options available to personalize cancer care today. Using a variety of advanced profiling technologies to assess relevant biological changes in each patient’s tumor, Caris Molecular Intelligence connects biomarker data generated from a tumor with biomarker-drug associations supported by evidence in the relevant clinical literature. Since 2009, Caris Life Sciences has tracked clinical and outcome data for certain patients undergoing tumor profiling, and has observed that patients treated with drugs consistent with their tumor profile show a significant increase in overall survival.  The company is also developing its ADAPT Biotargeting System™, a revolutionary and unbiased profiling platform with applications across therapy development, drug delivery, advanced diagnostics and disease monitoring. Currently being developed for cancer and other complex diseases, the ADAPT Biotargeting System is able to simultaneously measure millions of molecular interactions within complex biological systems in their natural state(s). Headquartered in Irving, Texas, Caris Life Sciences offers services throughout the U.S., Europe, Australia and other international markets. To learn more, please visit www.CarisLifeSciences.com.

    Media Inquiries:
    Caris Life Sciences Media Relations & Corporate Affairs

    CorpComm@carisls.com

    David Patti

    JFK Communications
    dpatti@jfkhealth.com
    609-456-0822

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